Protein Mass Spectrometry Sample Prep
Cayman Chemical SP-A196-215humntrIfl 5mg
A cephalosporin antibiotic building block binds to Hsp90B (Kd 6.201 UM) inhibits SREBP activation in a reporter assay using Hl 7702 cells at 40 UM inhibits palmitic acid- and oleic acid-induced increases in total cholesterol and triglyceride levels in HepG2 cells at 40 UM reduces hepatic steatosis in mice fed a high-fat diet from 5-25 mg/kg inhibits the growth of M. leprae in mice at 10 mg/kg a potential impurity in commercial preparations of cefoperazone
Sigma Organic Chemistry Lactic acid solution | 500G | 50-21-5 | MFCD00004520 | 85.0-90.0%
Lactic acid solution | 500G | 50-21-5 | MFCD00004520 | 85.0-90.0%
Cayman Chemical Sp-8-CPT-CyclIc AMPsodIum 5mg
A potent and selective inhibitor of JAK2 (IC50s 1 356 73 and 66 nM for JAK2 JAK1 JAK3 and TYK2 respectively) exhibits antiproliferative activity in cell lines engineered to express the JAK2V617F activating mutation (IC50s 60-70 nM)
Cayman Chemical Sp-8-CPT-CyclIc AMPsodIum 10mg
An inhibitor of PDE4 (IC50 0 10 M for the human recombinant enzyme)
Cayman Chemical CeramIdehydroxybovIn sp 50mg
A toxin used in GPCR and EAE research catalyzes the transfer of the ADP-ribose moiety of NAD to the a subunits of heterotrimeric Gi/o proteins uncoupling receptors from Gi/o proteins used as an adjuvant with specific antigens to induce EAE an animal model of multiple sclerosis
Cayman Chemical Sp-8-bromo-CyclIc AMPsodIu 5mg
An orally bioavailable pyridone derivative with antifibrotic anti-inflammatory and antioxidant activities inhibits TGF-B1-stimulated increases in collagen type I fibronectin and Hsp47 expression in A549 lung cancer cells in a concentration-dependent manner inhibits fibrosis and inhibits increases in collagen content fibrocyte pool size and the levels of chemokines CCL2 and CCL12 at 300 mg/kg in lung in a mouse model of pulmonary fibrosis induced by bleomycin inhibits fibrosis and increases in hepatocyte apoptosis lobular inflammation and hepatic expression of the fibrosis-related genes Col1a1 Timp1 Tgfb1 Pdgfb and Fgf2 in a mouse model of NASH at 280 mg/kg inhibits NADPH-dependent lipid peroxidation in sheep liver microsomes and scavenges hydroxyl radicals (IC50s ~6 and ~2.5 mM respectively)
Sigma Aldrich Fine Chemicals Biosciences NTA - Atto 550 BioReagent, suitable for fluorescence, >=80% (sum of isomers, HPCE) | 250UG
NTA - Atto 550 BioReagent, suitable for fluorescence, >=80% (sum of isomers, HPCE) | Purity: >=80% (sum of isomers, HPCE) | 250UG